Publications

Schwarz, E., Doan, N. T., Pergola, G., Westlye, L. T., Kaufmann, T., Wolfers, T., Brecheisen, R., Quarto, T., Ing, A. J., Di Carlo, P., Gurholt, T. P., Harms, R. L., Noirhomme, Q., Moberget, T., Agartz, I., Andreassen, O. A., Bellani, M., Bertolino, A., Blasi, G., Brambilla, P., Buitelaar, J. K., Cervenka, S., Flyckt, L., Frangou, S., Franke, B., Hall, J., Heslenfeld, D. J., Kirsch, P., McIntosh, A. M., Nöthen, M. M., Papassotiropoulos, A., de Quervain, D. J.-F., Rietschel, M., Schumann, G., Tost, H., Witt, S. H., Zink, M., Meyer-Lindenberg, A., & Imagemend Consortium, K. S. P. C. (2019). Reproducible grey matter patterns index a multivariate, global alteration of brain structure in schizophrenia and bipolar disorder. Translational Psychiatry, 9(1), 12. https://doi.org/10.1038/s41398-018-0225-4   edoc
Kaufmann, T., van der Meer, D., Doan, N. T., Schwarz, E., Lund, M. J., Agartz, I., Alnæs, D., Barch, D. M., Baur-Streubel, R., Bertolino, A., Bettella, F., Beyer, M. K., Bøen, E., Borgwardt, S., Brandt, C. L., Buitelaar, J., Celius, E. G., Cervenka, S., Conzelmann, A., Córdova-Palomera, A., Dale, A. M., de Quervain, D. J. F., Di Carlo, P., Djurovic, S., Dørum, E. S., Eisenacher, S., Elvsåshagen, T., Espeseth, T., Fatouros-Bergman, H., Flyckt, L., Franke, B., Frei, O., Haatveit, B., Håberg, A. K., Harbo, H. F., Hartman, C. A., Heslenfeld, D., Hoekstra, P. J., Høgestøl, E. A., Jernigan, T. L., Jonassen, R., Jönsson, E. G., Karolinska Schizophrenia Project, Kirsch, P., Kłoszewska, I., Kolskår, K. K., Landrø, N. I., Le Hellard, S., Lesch, K.-P., Lovestone, S., Lundervold, A., Lundervold, A. J., Maglanoc, L. A., Malt, U. F., Mecocci, P., Melle, I., Meyer-Lindenberg, A., Moberget, T., Norbom, L. B., Nordvik, J. E., Nyberg, L., Oosterlaan, J., Papalino, M., Papassotiropoulos, A., Pauli, P., Pergola, G., Persson, K., Richard, G., Rokicki, J., Sanders, A.-M., Selbæk, G., Shadrin, A. A., Smeland, O. B., Soininen, H., Sowa, P., Steen, V. M., Tsolaki, M., Ulrichsen, K. M., Vellas, B., Wang, L., Westman, E., Ziegler, G. C., Zink, M., Andreassen, O. A., & Westlye, L. T. (2019). Common brain disorders are associated with heritable patterns of apparent aging of the brain. Nature Neuroscience, 22(10), 1617-1623. https://doi.org/10.1038/s41593-019-0471-7   edoc
Loos, E., Egli, T., Coynel, D., Fastenrath, M., Freytag, V., Papassotiropoulos, A., de Quervain, D. J.-F., & Milnik, A. (2019). Predicting emotional arousal and emotional memory performance from an identical brain network. NeuroImage, 189, 459-467. https://doi.org/10.1016/j.neuroimage.2019.01.028   edoc
Aeberhard, A., Gschwind, L., Kossowsky, J., Luksys, G., Papassotiropoulos, A., de Quervain, D., & Vogler, C. (2019). Introducing COSMOS: a Web Platform for Multimodal Game-Based Psychological Assessment Geared Towards Open Science Practice. Journal of Technology in Behavioral Science, 4(3), 234-244.   
Wilker, S., Schneider, A., Conrad, D., Pfeiffer, A., Boeck, C., Lingenfelder, B., Freytag, V., Vukojevic, V., Vogler, C., Milnik, A., Papassotiropoulos, A., J.-F de Quervain, D., Elbert, T., Kolassa, S., & Kolassa, I.-T. (2018). Genetic variation is associated with PTSD risk and aversive memory: Evidence from two trauma-Exposed African samples and one healthy European sample. Translational Psychiatry, 8(251), 1-11. https://doi.org/10.1038/s41398-018-0297-1   edoc
Freytag, V., Vukojevic, V., Wagner-Thelen, H., Milnik, A., Vogler, C., Leber, M., Weinhold, L., Böhmer, A. C., Riedel-Heller, S., Maier, W., de Quervain, D. J.-F., Ramirez, A., & Papassotiropoulos, A. (2018). Genetic estimators of DNA methylation provide insights into the molecular basis of polygenic traits. Translational Psychiatry, 8(31), 1-13. https://doi.org/10.1038/s41398-017-0070-x   edoc
Egli, T., Coynel, D., Spalek, K., Fastenrath, M., Freytag, V., Heck, A., Loos, E., Auschra, B., Papassotiropoulos, A., de Quervain, D. J.-F., & Milnik, A. (2018). Identification of Two Distinct Working Memory-Related Brain Networks in Healthy Young Adults. ENeuro, 5(1), e0222-17.2018. https://doi.org/10.1523/ENEURO.0222-17.2018   edoc | Open Access
Conrad, D., Wilker, S., Schneider, A., Karabatsiakis, A., Pfeiffer, A., Kolassa, S., Freytag, V., Vukojevic, V., Vogler, C., Milnik, A., Papassotiropoulos, A., J.-F de Quervain, D., Elbert, T., & Kolassa, I.-T. (2018). Integrated genetic, epigenetic, and gene set enrichment analyses identify NOTCH as a potential mediator for PTSD risk after trauma: Results from two independent African cohorts. Psychophysiology, e13288. https://doi.org/10.1111/psyp.13288   edoc
van der Meer, D., Rokicki, J., Kaufmann, T., Córdova-Palomera, A., Moberget, T., Alnæs, D., Bettella, F., Frei, O., Doan, N. T., Sønderby, I. E., Smeland, O. B., Agartz, I., Bertolino, A., Bralten, J., Brandt, C. L., Buitelaar, J. K., Djurovic, S., van Donkelaar, M., Dørum, E. S., Espeseth, T., Faraone, S. V., Fernández, G., Fisher, S. E., Franke, B., Haatveit, B., Hartman, C. A., Hoekstra, P. J., Håberg, A. K., Jönsson, E. G., Kolskår, K. K., Le Hellard, S., Lund, M. J., Lundervold, A. J., Lundervold, A., Melle, I., Monereo Sánchez, J., Norbom, L. C., Nordvik, J. E., Nyberg, L., Oosterlaan, J., Papalino, M., Papassotiropoulos, A., Pergola, G., de Quervain, D. J. F., Richard, G., Sanders, A.-M., Selvaggi, P., Shumskaya, E., Steen, V. M., Tønnesen, S., Ulrichsen, K. M., Zwiers, M. P., Andreassen, O. A., Westlye, L. T., Alzheimer’s Disease Neuroimaging Initiative, Pediatric Imaging, N., & Genetics Study. (2018). Brain scans from 21,297 individuals reveal the genetic architecture of hippocampal subfield volumes. Molecular Psychiatry, 1-13. https://doi.org/10.1038/s41380-018-0262-7   edoc
Harrisberger, F., Smieskova, R., Egli, T., Simon, A. E., Riecher-Rössler, A., Fusar-Poli, P., Papassotiropoulos, A., & Borgwardt, S. (2018). Impact on the Onset of Psychosis of a Polygenic Schizophrenia-Related Risk Score and Changes in White Matter Volume. Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology, 48(3), 1201-1214. https://doi.org/10.1159/000491986   edoc | Open Access
Freytag, V., Probst, S., Hadziselimovic, N., Boglari, C., Hauser, Y., Peter, F., Gabor Fenyves, B., Milnik, A., Demougin, P., Vukojevic, V., de Quervain, D. J.-F., Papassotiropoulos, A., & Stetak, A. (2017). Genome-Wide Temporal Expression Profiling in Caenorhabditis elegans Identifies a Core Gene Set Related to Long-Term Memory. Journal of Neuroscience, 37(28), 6661-6672. https://doi.org/10.1523/JNEUROSCI.3298-16.2017   edoc
Atucha, E., Vukojevic, V., Fornari, R. V., Ronzoni, G., Demougin, P., Peter, F., Atsak, P., Coolen, M. W., Papassotiropoulos, A., McGaugh, J. L., de Quervain, D. J.-F., & Roozendaal, B. (2017). Noradrenergic activation of the basolateral amygdala maintains hippocampus-dependent accuracy of remote memory. Proceedings of the National Academy of Sciences, 114(34), 9176-9181. https://doi.org/10.1073/pnas.1710819114   edoc | Open Access
Egli, T., Vukojevic, V., Sengstag, T., Jacquot, M., Cabezón, R., Coynel, D., Freytag, V., Heck, A., Vogler, C., de Quervain, D. J.-F., Papassotiropoulos, A., & Milnik, A. (2017). Exhaustive search for epistatic effects on the human methylome. Scientific Reports, 7(1), 13669. https://doi.org/10.1038/s41598-017-13256-9   edoc | Open Access
Freytag, V., Carrillo-Roa, T., Milnik, A., Sämann, P. G., Vukojevic, V., Coynel, D., Demougin, P., Egli, T., Gschwind, L., Jessen, F., Loos, E., Maier, W., Riedel-Heller, S. G., Scherer, M., Vogler, C., Wagner, M., Binder, E. B., de Quervain, D. J.-F., & Papassotiropoulos, A. (2017). A peripheral epigenetic signature of immune system genes is linked to neocortical thickness and memory. Nature Communications, 8, 15193. https://doi.org/10.1038/ncomms15193   edoc | Open Access
Petrovska, J., Coynel, D., Fastenrath, M., Milnik, A., Auschra, B., Egli, T., Gschwind, L., Hartmann, F., Loos, E., Sifalakis, K., Vogler, C., de Quervain, D. J.-F., Papassotiropoulos, A., & Heck, A. (2017). The NCAM1 gene set is linked to depressive symptoms and their brain structural correlates in healthy individuals. Journal of Psychiatric Research, 91, 116-123. https://doi.org/10.1016/j.jpsychires.2017.03.007   edoc
Heck, A., Milnik, A., Vukojevic, V., Petrovska, J., Egli, T., Singer, J., Escobar, P., Sengstag, T., Coynel, D., Freytag, V., Fastenrath, M., Demougin, P., Loos, E., Hartmann, F., Schicktanz, N., Delarue Bizzini, B., Vogler, C., Kolassa, I.-T., Wilker, S., Elbert, T., Schwede, T., Beisel, C., Beerenwinkel, N., de Quervain, D. J.-F., & Papassotiropoulos, A. (2017). Exome sequencing of healthy phenotypic extremes links TROVE2 to emotional memory and PTSD. Nature Human Behaviour, 1(4), 81. https://doi.org/10.1038/s41562-017-0081   edoc
Milnik, A., Vogler, C., Demougin, P., Egli, T., Freytag, V., Hartmann, F., Heck, A., Peter, F., Spalek, K., Stetak, A., de Quervain, D. J.-F., Papassotiropoulos, A., & Vukojevic, V. (2016). Common epigenetic variation in a European population of mentally healthy young adults. Journal of Psychiatric Research, 83, 260-268. https://doi.org/10.1016/j.jpsychires.2016.08.012   edoc | Open Access
Harrisberger, F., Smieskova, R., Vogler, C., Egli, T., Schmidt, A., Lenz, C., Simon, A. E., Riecher-Rössler, A., Papassotiropoulos, A., & Borgwardt, S. (2016). Impact of polygenic schizophrenia-related risk and hippocampal volumes on the onset of psychosis. Translational Psychiatry, 6(8), e868. https://doi.org/10.1038/tp.2016.143   edoc | Open Access
Spalek, K., Coynel, D., Freytag, V., Hartmann, F., Heck, A., Milnik, A., de Quervain, D., & Papassotiropoulos, A. (2016). A common NTRK2 variant is associated with emotional arousal and brain white-matter integrity in healthy young subjects. Translational Psychiatry, 6, e758. https://doi.org/10.1038/tp.2016.20   edoc | Open Access
Hecker, T., Radtke, K. M., Hermenau, K., Papassotiropoulos, A., & Elbert, T. (2016). Associations among child abuse, mental health, and epigenetic modifications in the proopiomelanocortin gene (POMC): A study with children in Tanzania. Development and Psychopathology, 28(4/2), 1401-1412. https://doi.org/10.1017/S0954579415001248   edoc
Spalek, K., Fastenrath, M., Ackermann, S., Auschra, B., Coynel, D., Frey, J., Gschwind, L., Hartmann, F., van der Maarel, N., Papassotiropoulos, A., de Quervain, D., & Milnik, A. (2015). Sex-dependent dissociation between emotional appraisal and memory: a large-scale behavioral and fMRI study. Journal of Neuroscience, 35(3), 920-935. https://doi.org/10.1523/JNEUROSCI.2384-14.2015   edoc | Open Access
Luksys, G., Fastenrath, M., Coynel, D., Freytag, V., Gschwind, L., Heck, A., Jessen, F., Maier, W., Milnik, A., Riedel-Heller, S. G., Scherer, M., Spalek, K., Vogler, C., Wagner, M., Wolfsgruber, S., Papassotiropoulos, A., & de Quervain, D. J.-F. (2015). Computational dissection of human episodic memory reveals mental process-specific genetic profiles. Proceedings of the National Academy of Sciences of the United States of America, 112(35), E4939-E4948. https://doi.org/10.1073/pnas.1500860112   edoc | Open Access
Schicktanz, N., Fastenrath, M., Milnik, A., Spalek, K., Auschra, B., Nyffeler, T., Papassotiropoulos, A., de Quervain, D. J.-F., & Schwegler, K. (2015). Continuous theta burst stimulation over the left dorsolateral prefrontal cortex decreases medium load working memory performance in healthy humans. PLoS ONE, 10(3), e0120640. https://doi.org/10.1371/journal.pone.0120640   edoc | Open Access
Heck, A., Fastenrath, M., Coynel, D., Auschra, B., Bickel, H., Freytag, V., Gschwind, L., Hartmann, F., Jessen, F., Kaduszkiewicz, H., Maier, W., Milnik, A., Pentzek, M., Riedel-Heller, S. G., Spalek, K., Vogler, C., Wagner, M., Weyerer, S., Wolfsgruber, S., de Quervain, D. J.-F., & Papassotiropoulos, A. (2015). Genetic Analysis of Association Between Calcium Signaling and Hippocampal Activation, Memory Performance in the Young and Old, and Risk for Sporadic Alzheimer Disease. JAMA Psychiatry, 72(10), 1029-1036. https://doi.org/10.1001/jamapsychiatry.2015.1309   edoc | Open Access
Fastenrath, M., Coynel, D., Spalek, K., Milnik, A., Gschwind, L., Roozendaal, B., Papassotiropoulos, A., & de Quervain, D. J. F. (2014). Dynamic modulation of amygdala-hippocampal connectivity by emotional arousal. Journal of Neuroscience, 34(42), 13935-13947. https://doi.org/10.1523/JNEUROSCI.0786-14.2014   edoc | Open Access
Schicktanz, N., Schwegler, K., Fastenrath, M., Spalek, K., Milnik, A., Papassotiropoulos, A., Nyffeler, T., & de Quervain, D. J.-F. (2014). Motor threshold predicts working memory performance in healthy humans. Annals of Clinical and Translational Neurology, 1(1), 69-73. https://doi.org/10.1002/acn3.22   edoc | Open Access
Harrisberger, F., Spalek, K., Smieskova, R., Schmidt, A., Coynel, D., Milnik, A., Fastenrath, M., Freytag, V., Gschwind, L., Walter, A., Vogel, T., Bendfeldt, K., de Quervain, D. J.-F., Papassotiropoulos, A., & Borgwardt, S. (2014). The association of the BDNF Val66Met polymorphism and the hippocampal volumes in healthy humans : a joint meta-analysis of published and new data. Neuroscience and Biobehavioral Reviews, Vol. 42, 267-278. https://doi.org/10.1016/j.neubiorev.2014.03.011   edoc
Wilker, S., Elbert, T., Papassotiropoulos, A., de Quervain, D. J.-F., & Kolassa, I.-T. (2014). Responce to: Further Support for an Association between the Memory-Related Gene WWC1 and Posttraumatic Stress Disorder: Results from the Detroit Neighborhood Health Study. Biological psychiatry. Elsevier. https://doi.org/10.1016/j.biopsych.2014.05.003   edoc
Wilker, S., Pfeiffer, A., Kolassa, S., Elbert, T., Lingenfelder, B., Ovuga, E., Papassotiropoulos, A., de Quervain, D., & Kolassa, I.-T. (2014). The role of FKBP5 genotype in moderating long-term effectiveness of exposure-based psychotherapy for posttraumatic stress disorder. Translational Psychiatry, 4, e403. https://doi.org/10.1038/tp.2014.49   edoc | Open Access
Vogler, C., Gschwind, L., Coynel, D., Freytag, V., Milnik, A., Egli, T., Heck, A., de Quervain, D. J.-F., & Papassotiropoulos, A. (2014). Substantial SNP-based heritability estimates for working memory performance. Translational Psychiatry, 4(9), e438. https://doi.org/10.1038/tp.2014.81   edoc | Open Access
Vukojevic, V., Kolassa, I.-T., Fastenrath, M., Gschwind, L., Spalek, K., Milnik, A., Heck, A., Vogler, C., Wilker, S., Demougin, P., Peter, F., Atucha, E., Stetak, A., Roozendaal, B., Elbert, T., Papassotiropoulos, A., & de Quervain, D. J.-F. (2014). Epigenetic modification of the glucocorticoid receptor gene is linked to traumatic memory and post-traumatic stress disorder risk in genocide survivors. Journal of Neuroscience, 34(31), 10274-10284. https://doi.org/10.1523/JNEUROSCI.1526-14.2014   edoc | Open Access
Heck, A., Fastenrath, M., Ackermann, S., Auschra, B., Bickel, H., Coynel, D., Gschwind, L., Jessen, F., Kaduszkiewicz, H., Maier, W., Milnik, A., Pentzek, M., Riedel-Heller, S. G., Ripke, S., Spalek, K., Sullivan, P., Vogler, C., Wagner, M., Weyerer, S., Wolfsgruber, S., de Quervain, D. J.-F., & Papassotiropoulos, A. (2014). Converging genetic and functional brain imaging evidence links neuronal excitability to working memory, psychiatric disease, and brain activity. Neuron, 81(5), 1203-1213. https://doi.org/10.1016/j.neuron.2014.01.010   edoc | Open Access
Hadziselimovic, N., Vukojevic, V., Peter, F., Milnik, A., Fastenrath, M., Fenyves, B. G., Hieber, P., Demougin, P., Vogler, C., de Quervain, D. J.-F., Papassotiropoulos, A., & Stetak, A. (2014). Forgetting is regulated via Musashi-mediated translational control of the Arp2/3 complex. Cell, 156(6), 1153-1166. https://doi.org/10.1016/j.cell.2014.01.054   edoc
Papassotiropoulos, A., Gerhards, C., Heck, A., Ackermann, S., Aerni, A., Schicktanz, N., Auschra, B., Demougin, P., Mumme, E., Elbert, T., Ertl, V., Gschwind, L., Hanser, E., Huynh, K.-D., Jessen, F., Kolassa, I.-T., Milnik, A., Paganetti, P., Spalek, K., Vogler, C., Muhs, A., Pfeifer, A., & de Quervain, D. J.-F. (2013). Human genome-guided identification of memory-modulating drugs. Proceedings of the National Academy of Sciences of the United States of America, 110(46), E4369-E4374. https://doi.org/10.1073/pnas.1314478110   edoc | Open Access
Ackermann, S., Hartmann, F., Papassotiropoulos, A., de Quervain, D. J.-F., & Rasch, B. (2013). Associations between Basal Cortisol Levels and Memory Retrieval in Healthy Young Individuals. Journal of Cognitive Neuroscience, 25(11), 1896-1907. https://doi.org/10.1162/jocn_a_00440   edoc
Easton, A. C., Lourdusamy, A., Loth, E., Toro, R., Giese, K. P., Kornhuber, J., de Quervain, D. J.-F., Papassotiropoulos, A., Fernandes, C., Müller, C. P., & Schumann, G. (2013). CAMK2A polymorphisms predict working memory performance in humans. Molecular Psychiatry, 18(8), 850-852. https://doi.org/10.1038/mp.2012.114   edoc
Wilker, S., Kolassa, S., Vogler, C., Lingenfelder, B., Elbert, T., Papassotiropoulos, A., de Quervain, D. J.-F., & Kolassa, I.-T. (2013). The role of memory-related gene WWC1 (KIBRA) in lifetime posttraumatic stress disorder : evidence from two independent samples from African conflict regions. Biological Psychiatry, 74(9), 664-671. https://doi.org/10.1016/j.biopsych.2013.02.022   edoc
Papassotiropoulos, A., Stefanova, E., Vogler, C., Gschwind, L., Ackermann, S., Spalek, K., Rasch, B., Heck, A., Aerni, A., Hanser, E., Demougin, P., Huynh, K.-D., Luechinger, R., Klarhöfer, M., Novakovic, I., Kostic, V., Boesiger, P., Scheffler, K., & de Quervain, D. J.-F. (2013). A genome-wide survey and functional brain imaging study identify CTNNBL1 as a memory-related gene. Molecular Psychiatry, 18(2), 255-263. https://doi.org/10.1038/mp.2011.148   edoc | Open Access
Ackermann, S., Spalek, K., Rasch, B., Gschwind, L., Coynel, D., Fastenrath, M., Papassotiropoulos, A., & de Quervain, D. J.-F. (2012). Testosterone levels in healthy men are related to amygdala reactivity and memory performance. Psychoneuroendocrinology, 37(9), 1417-1424. https://doi.org/10.1016/j.psyneuen.2012.01.008   edoc
Vukojevic, V., Gschwind, L., Vogler, C., Demougin, P., de Quervain, D. J.-F., Papassotiropoulos, A., & Stetak, A. (2012). A role for alpha-adducin (ADD-1) in nematode and human memory. The EMBO Journal, 31(6), 1453-1466.   edoc | Open Access
Mata, R., Hau, R., Papassotiropoulos, A., & Hertwig, R. (2012). DAT1 polymorphism is associated with risk taking in the Balloon Analogue Risk Task (BART). PLoS ONE, 7(6), e39135. https://doi.org/10.1371/journal.pone.0039135   edoc
Milnik, A., Heck, A., Vogler, C., Heinze, H. J., de Quervain, D. J., & Papassotiropoulos, A. (2012). Association of KIBRA with episodic and working memory: a meta-analysis. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 159B(8), 958-969. https://doi.org/10.1002/ajmg.b.32101   edoc
de Quervain, D. J.-F., Kolassa, I.-T., Ackermann, S., Aerni, A., Boesiger, P., Demougin, P., Elbert, T., Ertl, V., Gschwind, L., Hadziselimovic, N., Hanser, E., Heck, A., Hieber, P., Huynh, K.-D., Klarhöfer, M., Luechinger, R., Rasch, B., Scheffler, K., Spalek, K., Stippich, C., Vogler, C., Vukojevic, V., Stetak, A., & Papassotiropoulos, A. (2012). PKCα is genetically linked to memory capacity in healthy subjects and to risk for posttraumatic stress disorder in genocide survivors. Proceedings of the National Academy of Sciences of the United States of America, 109(22), 8746-8751. https://doi.org/10.1073/pnas.1200857109   edoc | Open Access
Heck, A., Vogler, C., Gschwind, L., Ackermann, S., Auschra, B., Spalek, K., Rasch, B., de Quervain, D., & Papassotiropoulos, A. (2011). Statistical epistasis and functional brain imaging support a role of voltage-gated potassium channels in human memory. PLoS ONE, 6(12), e29337. https://doi.org/10.1371/journal.pone.0029337   edoc | Open Access
Papassotiropoulos, A., Henke, K., Stefanova, E., Aerni, A., Müller, A., Demougin, P., Vogler, C., Sigmund, J. C., Gschwind, L., Huynh, K.-D., Coluccia, D., Mondadori, C. R., Hänggi, J., Buchmann, A., Kostic, V., Novakovic, I., van den Bussche, H., Kaduszkiewicz, H., Weyerer, S., Bickel, H., Riedel-Heller, S., Pentzek, M., Wiese, B., Dichgans, M., Wagner, M., Jessen, F., Maier, W., & de Quervain, D. J.-F. (2011). A genome-wide survey of human short-term memory. Molecular Psychiatry, 16(2), 184-192. https://doi.org/10.1038/mp.2009.133   edoc | Open Access
Papassotiropoulos, A., & de Quervain, D. J.-F. (2011). Genetics of human episodic memory : dealing with complexity. Trends in Cognitive Sciences, 15(9), 381-387. https://doi.org/10.1016/j.tics.2011.07.005   edoc
Hauer, D., Weis, F., Papassotiropoulos, A., Schmoeckel, M., Beiras-Fernandez, A., Lieke, J., Kaufmann, I., Kirchhoff, F., Vogeser, M., Roozendaal, B., Briegel, J., de Quervain, D., & Schelling, G. (2011). Relationship of a common polymorphism of the glucocorticoid receptor gene to traumatic memories and posttraumatic stress disorder in patients after intensive care therapy. Critical Care Medicine, 39(4), 643-650. https://doi.org/10.1097/CCM.0b013e318206bae6   
Schneider, A., Falkai, P., & Papassotiropoulos, A. (2010). Molekulare Grundlagen Tau-Protein-vermittelter Toxizität : neue experimentelle Therapiestrategien zur Behandlung der Alzheimer-Erkrankung. Nervenarzt. Springer. https://doi.org/10.1007/s00115-010-3052-2   edoc
Thal, D. R., Papassotiropoulos, A., Saido, T. C., Griffin, W. S. T., Mrak, R. E., Kölsch, H., Del Tredici, K., Attems, J., & Ghebremedhin, E. (2010). Capillary cerebral amyloid angiopathy identifies a distinct APOE epsilon4-associated subtype of sporadic Alzheimer’s disease. Acta Neuropathologica, 120(2), 169-183.   edoc
Webster, J., Reiman, E. M., Zismann, V. L., Joshipura, K. D., Pearson, J. V., Hu-Lince, D., Huentelman, M. J., Craig, D. W., Coon, K. D., Beach, T., Rohrer, K. C., Zhao, A. S., Leung, D., Bryden, L., Marlowe, L., Kaleem, M., Mastroeni, D., Grover, A., Rogers, J., Heun, R., Jessen, F., Kölsch, H., Heward, C. B., Ravid, R., Hutton, M. L., Melquist, S., Petersen, R. C., Caselli, R. J., Papassotiropoulos, A., Stephan, D. A., Hardy, J., & Myers, A. (2010). Whole genome association analysis shows that ACE is a risk factor for Alzheimer’s disease and fails to replicate most candidates from Meta-analysis. International Journal of Molecular Epidemiology and Genetics, Vol. 1, H. 1, 19-30.   edoc
Rasch, B., Papassotiropoulos, A., & de Quervain, D.-F. (2010). Imaging genetics of cognitive functions : Focus on episodic memory. NeuroImage, 53(3), 870-877. https://doi.org/10.1016/j.neuroimage.2010.01.001   edoc
Kolassa, I.-T., Ertl, V., Eckart, C., Glöckner, F., Kolassa, S., Papassotiropoulos, A., de Quervain, D. J.-F., & Elbert, T. (2010). Association study of trauma load and SLC6A4 promoter polymorphism in posttraumatic stress disorder : evidence from survivors of the Rwandan genocide. The Journal of Clinical Psychiatry, 71(5), 543-547. https://doi.org/10.4088/JCP.08m04787blu   edoc
Rasch, B., Spalek, K., Buholzer, S., Luechinger, R., Boesiger, P., de Quervain, D. J.-F., & Papassotiropoulos, A. (2010). Aversive stimuli lead to differential amygdala activation and connectivity patterns depending on catechol-O-methyltransferase Val158Met genotype. NeuroImage, 52(4), 1712-1719. https://doi.org/10.1016/j.neuroimage.2010.05.054   edoc
Dill, M. T., Duong, F. H., Vogt, J. E., Bibert, S., Bochud, P. Y., Terracciano, L., Papassotiropoulos, A., Roth, V., & Heim, M. H. (2010). Interferon-Induced Gene Expression Is a Stronger Predictor of Treatment Response than IL28B Genotype in Patients with Hepatitis C. Gastroenterology, 140(3), 1021-1031. https://doi.org/10.1053/j.gastro.2010.11.039   edoc
Vogler, C., Gschwind, L., Röthlisberger, B., Huber, A., Filges, I., Miny, P., Auschra, B., Stetak, A., Demougin, P., Vukojevic, V., Kolassa, I.-T., Elbert, T., de Quervain, D. J.-F., & Papassotiropoulos, A. (2010). Microarray-based maps of copy-number variant regions in European and sub-saharan populations. PLoS ONE, 5(12), e15246. https://doi.org/10.1371/journal.pone.0015246    edoc | Open Access
Cathomas, F., Vogler, C., Euler-Sigmund, J. C., de Quervain, D. J.-F., & Papassotiropoulos, A. (2010). Fine-mapping of the brain-derived neurotrophic factor (BDNF) gene supports an association of the Val66Met polymorphism with episodic memory. International Journal of Neuropsychopharmacology : Official Scientific Journal of the Collegium Internationale Neuro-Psychopharmacologicum, 13(8), 975-980. https://doi.org/10.1017/S1461145710000519   edoc | Open Access
Rasch, B., Spalek, K., Buholzer, S., Luechinger, R., Boesiger, P., Papassotiropoulos, A., & de Quervain, D. J.-F. (2009). A genetic variation of the noradrenergic system is related to differential amygdala activation during encoding of emotional memories. Proceedings of the National Academy of Sciences of the United States of America, 106(45), 19191-19196. https://doi.org/10.1073/pnas.0907425106   edoc | Open Access
Vogler, C., Spalek, K., Aerni, A., Demougin, P., Müller, A., Huynh, K.-D., Papassotiropoulos, A., & de Quervain, D. J.-F. (2009). CPEB3 is associated with human episodic memory. Frontiers in Behavioral Neuroscience, 3(4). https://doi.org/10.3389/neuro.08.004.2009   edoc | Open Access
Hoerndli, F. J., Walser, M., Fröhli Hoier, E., de Quervain, D., Papassotiropoulos, A., & Hajnal, A. (2009). A conserved function of C. elegans CASY-1 calsyntenin in associative learning. PLoS ONE, 4(3), e4880. https://doi.org/10.1371/journal.pone.0004880   edoc | Open Access
Kolassa, I.-T., Kolassa, S., Ertl, V., Papassotiropoulos, A., & De Quervain, D. J.-F. (2009). The Risk of Posttraumatic Stress Disorder After Trauma Depends on Traumatic Load and the Catechol-O-Methyltransferase Val(158)Met Polymorphism. Biological Psychiatry, 67(4), 304-308. https://doi.org/10.1016/j.biopsych.2009.10.009   edoc
Tagarakis, G. I., Tsolaki-Tagaraki, F., Tsolaki, M., Diegeler, A., Stylianakis, G. E., Kazis, D., Tsilimingas, N. B., & Papassotiropoulos, A. (2008). Are genetic components related to cognitive decline after coronary artery surgery? : Genetics and brain function after bypass heart surgery. Journal of cardiac surgery. Wiley-Blackwell.   edoc
Corneveaux, J. J., Liang, W. S., Reiman, E. M., Webster, J. A., Myers, A. J., Zismann, V. L., Joshipura, K. D., Pearson, J. V., Hu-Lince, D., Craig, D. W., Coon, K. D., Dunckley, T., Bandy, D., Lee, W., Chen, K., Beach, T. G., Mastroeni, D., Grover, A., Ravid, R., Sando, S. B., Aasly, J. O., Heun, R., Jessen, F., Kölsch, H., Rogers, J., Hutton, M. L., Melquist, S., Petersen, R. C., Alexander, G. E., Caselli, R. J., Papassotiropoulos, A., Stephan, D. A., & Huentelman, M. J. (2008). Evidence for an association between KIBRA and late-onset Alzheimer’s disease. Neurobiology of Aging, 31(6), 901-909.   edoc
Reiman, E. M., Chen, K., Caselli, R. J., Alexander, G. E., Bandy, D., Adamson, J. L., Lee, W., Cannon, A., Stephan, E. A., Stephan, D. A., & Papassotiropoulos, A. (2008). Cholesterol-related genetic risk scores are associated with hypometabolism in Alzheimer’s-affected brain regions. NeuroImage, 40(3), 1214-1221.   edoc
Webster, J. A., Myers, A. J., Pearson, J. V., Craig, D. W., Hu-Lince, D., Coon, K. D., Zismann, V. L., Beach, T., Leung, D., Bryden, L., Halperin, R. F., Marlowe, L., Kaleem, M., Huentelman, M. J., Joshipura, K., Walker, D., Heward, C. B., Ravid, R., Rogers, J., Papassotiropoulos, A., Hardy, J., Reiman, E. M., & Stephan, D. A. (2008). Sorl1 as an Alzheimer’s disease predisposition gene?. Neuro-Degenerative Diseases, 5(2), 60-64. https://doi.org/10.1159/000110789   edoc | Open Access
Tagarakis, G. I., Tsolaki-Tagaraki, F., Tsolaki, M., Diegeler, A., Tsilimingas, N. B., & Papassotiropoulos, A. (2007). The role of apolipoprotein E in cognitive decline and delirium after bypass heart operations. American Journal of Alzheimer’s Disease and Other Dementias, 22(3), 223-228.   edoc
Huentelman, M. J., Papassotiropoulos, A., Craig, D. W., Hoerndli, F. J., Pearson, J. V., Huynh, K.-D., Corneveaux, J., Hänggi, J., Mondadori, C. R. A., Buchmann, A., Reiman, E. M., Henke, K., de Quervain, D. J.-F., & Stephan, D. A. (2007). Calmodulin-binding transcription activator 1 (CAMTA1) alleles predispose human episodic memory performance. Human Molecular Genetics, 16(12), 1469-1477. https://doi.org/10.1093/hmg/ddm097   edoc
Coon, K. D., Myers, A. J., Craig, D. W., Webster, J. A., Pearson, J. V., Lince, D. H., Zismann, V. L., Beach, T. G., Leung, D., Bryden, L., Halperin, R. F., Marlowe, L., Kaleem, M., Walker, D. G., Ravid, R., Heward, C. B., Rogers, J., Papassotiropoulos, A., Reiman, E. M., Hardy, J., & Stephan, D. A. (2007). A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer’s disease. The Journal of Clinical Psychiatry, 68(4), 613-618.   edoc
Wollmer, M. A., Sleegers, K., Ingelsson, M., Zekanowski, C., Brouwers, N., Maruszak, A., Brunner, F., Huynh, K.-D., Kilander, L., Brundin, R.-M., Hedlund, M., Giedraitis, V., Glaser, A., Engelborghs, S., De Deyn, P. P., Kapaki, E., Tsolaki, M., Daniilidou, M., Molyva, D., Paraskevas, G. P., Thal, D. R., Barcikowska, M., Kuznicki, J., Lannfelt, L., Van Broeckhoven, C., Nitsch, R. M., Hock, C., & Papassotiropoulos, A. (2007). Association study of cholesterol-related genes in Alzheimer’s disease. Neurogenetics, 8(3), 179-188.   edoc
Tagarakis, G. I., Tsolaki-Tagaraki, F., Tsolaki, M., Diegeler, A., Kazis, D., Rouska, E., & Papassotiropoulos, A. (2007). The role of SOAT-1 polymorphisms in cognitive decline and delirium after bypass heart surgery. Clinical Research in Cardiology, 96(9), 600-603.   edoc
Mondadori, C. R. A., de Quervain, D. J.-F., Buchmann, A., Mustovic, H., Wollmer, M. A., Schmidt, C. F., Boesiger, P., Hock, C., Nitsch, R. M., Papassotiropoulos, A., & Henke, K. (2007). Better memory and neural efficiency in young apolipoprotein E epsilon4 carriers. Cerebral Cortex, 17(8), 1934-1947. https://doi.org/10.1093/cercor/bhl103   edoc
Pearson, J. V., Huentelman, M. J., Halperin, R. F., Tembe, W. D., Melquist, S., Homer, N., Brun, M., Szelinger, S., Coon, K. D., Zismann, V. L., Webster, J. A., Beach, T., Sando, S. B., Aasly, J. O., Heun, R., Jessen, F., Kolsch, H., Tsolaki, M., Daniilidou, M., Reiman, E. M., Papassotiropoulos, A., Hutton, M. L., Stephan, D. A., & Craig, D. W. (2007). Identification of the genetic basis for complex disorders by use of pooling-based genomewide single-nucleotide-polymorphism association studies. American Journal of Human Genetics, 80(1), 126-139.   edoc
De Ferrari, G. V., Papassotiropoulos, A., Biechele, T., Wavrant De-Vrieze, F., Avila, M. E., Major, M. B., Myers, A., Sáez, K., Henríquez, J. P., Zhao, A., Wollmer, M. A., Nitsch, R. M., Hock, C., Morris, C. M., Hardy, J., & Moon, R. T. (2007). Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer’s disease. Proceedings of the National Academy of Sciences of the United States of America, 104(22), 9434-9439.   edoc
Reiman, E. M., Webster, J. A., Myers, A. J., Hardy, J., Dunckley, T., Zismann, V. L., Joshipura, K. D., Pearson, J. V., Hu-Lince, D., Huentelman, M. J., Craig, D. W., Coon, K. D., Liang, W. S., Herbert, R. H., Beach, T., Rohrer, K. C., Zhao, A. S., Leung, D., Bryden, L., Marlowe, L., Kaleem, M., Mastroeni, D., Grover, A., Heward, C. B., Ravid, R., Rogers, J., Hutton, M. L., Melquist, S., Petersen, R. C., Alexander, G. E., Caselli, R. J., Kukull, W., Papassotiropoulos, A., & Stephan, D. A. (2007). GAB2 alleles modify Alzheimer’s risk in APOE epsilon4 carriers. Neuron, 54(5), 713-720.   edoc
de Quervain, D. J.-F., Kolassa, I.-T., Ertl, V., Onyut, P. L., Neuner, F., Elbert, T., & Papassotiropoulos, A. (2007). A deletion variant of the alpha2b-adrenoceptor is related to emotional memory in Europeans and Africans. Nature Neuroscience, 10(9), 1137-1139. https://doi.org/10.1038/nn1945   edoc
Hoerndli, F. J., Pelech, S., Papassotiropoulos, A., & Götz, J. (2007). Aβ treatment and P301L tau expression in an Alzheimer’s disease tissue culture model act synergistically to promote aberrant cell cycle re-entry. The European Journal of Neuroscience, 26(1), 60-72.   edoc
Coon, K. D., Siegel, A. M., Yee, S. J., Dunckley, T. L., Mueller, C., Nagra, R. M., Tourtellotte, W. W., Reiman, E. M., Papassotiropoulos, A., Petersen, F. F., Stephan, D. A., & Kirsch, W. M. (2006). Preliminary demonstration of an allelic association of the IREB2 gene with Alzheimer’s disease. Journal of Alzheimer’s Disease, 9(3), 225-233.   edoc
Wollmer, M. A., Kapaki, E., Hersberger, M., Muntwyler, J., Brunner, F., Tsolaki, M., Akatsu, H., Kosaka, K., Michikawa, M., Molyva, D., Paraskevas, G. P., Lütjohann, D., von Eckardstein, A., Hock, C., Nitsch, R. M., & Papassotiropoulos, A. (2006). Ethnicity-dependent genetic association of ABCA2 with sporadic Alzheimer’s disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, Vol. 141B, H. 5, 534-536.   edoc
Coon, K. D., Valla, J., Szelinger, S., Schneider, L. E., Niedzielko, T. L., Brown, K. M., Pearson, J. V., Halperin, R., Dunckley, T., Papassotiropoulos, A., Caselli, R. J., Reiman, E. M., & Stephan, D. A. (2006). Quantitation of heteroplasmy of mtDNA sequence variants identified in a population of AD patients and controls by array-based resequencing. Mitochondrion, 6(4), 194-210.   edoc
Papassotiropoulos, A., Stephan, D. A., Huentelman, M. J., Hoerndli, F. J., Craig, D. W., Pearson, J. V., Huynh, K.-D., Brunner, F., Corneveaux, J., Osborne, D., Wollmer, M. A., Aerni, A., Coluccia, D., Hänggi, J., Mondadori, C. R. A., Buchmann, A., Reiman, E. M., Caselli, R. J., Henke, K., & de Quervain, D. J.-F. (2006). Common Kibra alleles are associated with human memory performance. Science, 314(5798), 475-478. https://doi.org/10.1126/science.1129837   edoc
de Quervain, D. J.-F., & Papassotiropoulos, A. (2006). Identification of a genetic cluster influencing memory performance and hippocampal activity in humans. Proceedings of the National Academy of Sciences of the United States of America, 103(11), 4270-4274. https://doi.org/10.1073/pnas.0510212103   edoc
Papassotiropoulos, A., Fountoulakis, M., Dunckley, T., Stephan, D. A., & Reiman, E. M. (2006). Genetics, transcriptomics, and proteomics of Alzheimer’s disease. The Journal of Clinical Psychiatry, 67(4), 652-670.   edoc
Wollmer, M. A., Nitsch, R. M., Hock, C., & Papassotiropoulos, A. (2006). Genetic association study on colony-stimulating factor 1 in Alzheimer’s disease. Neuro-Degenerative Diseases, 3(6), 334-337. https://doi.org/10.1159/000097302   edoc | Open Access
Papassotiropoulos, A., Tsolaki, M., Wollmer, M. A., Molyva, D., Thal, D. R., Huynh, K.-D., Tracy, J., Staehelin, H. B., Monsch, A. U., Nitsch, R. M., & Hock, C. (2005). No association of a non-synonymous PLAU polymorphism with Alzheimer’s disease and disease-related traits. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, Vol. 132B, H. 1, 21-23.   edoc
Papassotiropoulos, A., Henke, K., Aerni, A., Coluccia, D., Garcia, E., Wollmer, M. A., Huynh, K.-D., Monsch, A. U., Stähelin, H. B., Hock, C., Nitsch, R. M., & de Quervain, D. J.-F. (2005). Age-dependent effects of the 5-hydroxytryptamine-2a-receptor polymorphism (His452Tyr) on human memory. NeuroReport, 16(8), 839-842.   edoc
Kornblum, C., Schröder, R., Müller, K., Vorgerd, M., Eggers, J., Bogdanow, M., Papassotiropoulos, A., Fabian, K., Klockgether, T., & Zange, J. (2005). Creatine has no beneficial effect on skeletal muscle energy metabolism in patients with single mitochondrial DNA deletions : a placebo-controlled, double-blind 31P-MRS crossover study. European Journal of Neurology, 12(4), 300-309.   edoc
Papassotiropoulos, A., Wollmer, M. A., Aguzzi, A., Hock, C., Nitsch, R. M., & de Quervain, D. J.-F. (2005). The prion gene is associated with human long-term memory. Human Molecular Genetics, 14(15), 2241-2246. https://doi.org/10.1093/hmg/ddi228   edoc
Papassotiropoulos, A., Wollmer, M. A., Tsolaki, M., Brunner, F., Molyva, D., Lütjohann, D., Nitsch, R. M., & Hock, C. (2005). A cluster of cholesterol-related genes confers susceptibility for Alzheimer’s disease. The Journal of Clinical Psychiatry, 66(7), 940-947.   edoc
Koller, M. F., Papassotiropoulos, A., Henke, K., Behrends, B., Noda, S., Kratzer, A., Hock, C., & Hofmann, M. (2005). Evidence of a genetic basis of Morgagni-Stewart-Morel syndrome : a case report of identical twins. Neuro-degenerative Diseases. Karger. https://doi.org/10.1159/000089284   edoc | Open Access
Papassotiropoulos, A., Lambert, J.-C., Wavrant-De Vrièze, F., Wollmer, M. A., von der Kammer, H., Streffer, J. R., Maddalena, A., Huynh, K.-D., Wolleb, S., Lutjohann, D., Schneider, B., Thal, D. R., Grimaldi, L. M. E., Tsolaki, M., Kapaki, E., Ravid, R., Konietzko, U., Hegi, T., Pasch, T., Jung, H., Braak, H., Amouyel, P., Rogaev, E. I., Hardy, J., Hock, C., & Nitsch, R. M. (2005). Cholesterol 25-hydroxylase on chromosome 10q is a susceptibility gene for sporadic Alzheimer’s disease. Neuro-Degenerative Diseases, 2(5), 233-241. https://doi.org/10.1159/000090362   edoc | Open Access
Aerni, A., Traber, R., Hock, C., Roozendaal, B., Schelling, G., Papassotiropoulos, A., Nitsch, R. M., Schnyder, U., & de Quervain, D. J.-F. (2004). Low-dose cortisol for symptoms of posttraumatic stress disorder. American Journal of Psychiatry. American Psychiatric Association. https://doi.org/10.1176/appi.ajp.161.8.1488   edoc
de Quervain, D. J.-F., Poirier, R., Wollmer, M. A., Grimaldi, L. M. E., Tsolaki, M., Streffer, J. R., Hock, C., Nitsch, R. M., Mohajeri, M. H., & Papassotiropoulos, A. (2004). Glucocorticoid-related genetic susceptibility for Alzheimer’s disease. Human Molecular Genetics, 13(1), 47-52. https://doi.org/10.1093/hmg/ddg361   edoc
Alberici, A., Gobbo, C., Panzacchi, A., Nicosia, F., Ghidoni, R., Benussi, L., Hock, C., Papassotiropoulos, A., Liberini, P., Growdon, J. H., Frisoni, G. B., Villa, A., Zanetti, O., Cappa, S., Fazio, F., & Binetti, G. (2004). Frontotemporal dementia : impact of P301L tau mutation on a healthy carrier. Journal of Neurology, Neurosurgery, and Psychiatry, 75(11), 1607-1610.   edoc
Chen, F., Wollmer, M. A., Hoerndli, F., Münch, G., Kuhla, B., Rogaev, E. I., Tsolaki, M., Papassotiropoulos, A., & Götz, J. (2004). Role for glyoxalase I in Alzheimer’s disease. Proceedings of the National Academy of Sciences of the United States of America, 101(20), 7687-7692.   edoc
Maddalena, A. S., Papassotiropoulos, A., Gonzalez-Agosti, C., Signorell, A., Hegi, T., Pasch, T., Nitsch, R. M., & Hock, C. (2004). Cerebrospinal fluid profile of amyloid beta peptides in patients with Alzheimer’s disease determined by protein biochip technology. Neuro-Degenerative Diseases, 1(4-5), 231-235. https://doi.org/10.1159/000080991   edoc | Open Access
Streffer, J. R., Papassotiropoulos, A., Kurosinski, P., Signorell, A., Wollmer, M. A., Tsolaki, M., Iakovidou, V., Hörndli, F., Bosset, J., Götz, J., Nitsch, R. M., & Hock, C. (2003). Saitohin gene is not associated with Alzheimer’s disease. Journal of Neurology, Neurosurgery, and Psychiatry, 74(3), 362-363.   edoc
Schmidt, S., Papassotiropoulos, A., Sotgiu, S., Kölsch, H., Arru, G., Fois, M. L., Haase, C. G., Schmitz, S., König, N., Harzheim, M., Heun, R., & Klockgether, T. (2003). Investigation of a genetic variation of a variable number tandem repeat polymorphism of interleukin-6 gene in patients with multiple sclerosis. Journal of Neurology, 250(5), 607-611.   edoc
Papassotiropoulos, A., Streffer, J. R., Tsolaki, M., Schmid, S., Thal, D., Nicosia, F., Iakovidou, V., Maddalena, A., Lütjohann, D., Ghebremedhin, E., Hegi, T., Pasch, T., Träxler, M., Brühl, A., Benussi, L., Binetti, G., Braak, H., Nitsch, R. M., & Hock, C. (2003). Increased brain beta-amyloid load, phosphorylated tau, and risk of Alzheimer disease associated with an intronic CYP46 polymorphism. Archives of Neurology, 60(1), 29-35.   edoc
Schmidt, S., Marrosu, G. M., Kölsch, H., Haase, C. G., Ferenczik, S., Sokolowski, P., Köhler, W., Schmidt, M., Papassotiropoulos, A., Heun, R., Grosse-Wilde, H., & Klockgether, T. (2003). Genetic variations and humoral immune responses to myelin oligodendroglia glycoprotein in adult phenotypes of X-linked adrenoleukodystrophy. Journal of Neuroimmunology, 135(1-2), 148-153.   edoc
Wollmer, M. A., Streffer, J. R., Lütjohann, D., Tsolaki, M., Iakovidou, V., Hegi, T., Pasch, T., Jung, H. H., Bergmann, K. von, Nitsch, R. M., Hock, C., & Papassotiropoulos, A. (2003). ABCA1 modulates CSF cholesterol levels and influences the age at onset of Alzheimer’s disease. Neurobiology of Aging, 24(3), 421-426.   edoc
Bagli, M., Papassotiropoulos, A., Hampel, H., Becker, K., Jessen, F., Bürger, K., Ptok, U., Rao, M. L., Möller, H.-J., Maier, W., & Heun, R. (2003). Polymorphisms of the gene encoding the inflammatory cytokine interleukin-6 determine the magnitude of the increase in soluble interleukin-6 receptor levels in Alzheimer’s disease : Results of a pilot study. European Archives of Psychiatry and Clinical Neuroscience, 253(1), 44-48.   edoc
Wollmer, M. A., Streffer, J. R., Tsolaki, M., Grimaldi, L. M. E., Lütjohann, D., Thal, D., von Bergmann, K., Nitsch, R. M., Hock, C., & Papassotiropoulos, A. (2003). Genetic association of acyl-coenzyme A : cholesterol acyltransferase with cerebrospinal fluid cholesterol levels, brain amyloid load, and risk for Alzheimer’s disease. Molecular Psychiatry, 8(6), 635-638.   edoc
Maddalena, A., Papassotiropoulos, A., Müller-Tillmanns, B., Jung, H. H., Hegi, T., Nitsch, R. M., & Hock, C. (2003). Biochemical diagnosis of Alzheimer disease by measuring the cerebrospinal fluid ratio of phosphorylated tau protein to beta-amyloid peptide42. Archives of Neurology, 60(9), 1202-1206.   edoc
de Quervain, D. J.-F., Henke, K., Aerni, A., Coluccia, D., Wollmer, M. A., Hock, C., Nitsch, R. M., & Papassotiropoulos, A. (2003). A functional genetic variation of the 5-HT2a receptor affects human memory. Nature Neuroscience, 6(11), 1141-1142. https://doi.org/10.1038/nn1146   edoc
Hock, C., Konietzko, U., Streffer, J. R., Tracy, J., Signorell, A., Müller-Tillmanns, B., Lemke, U., Henke, K., Moritz, E., Garcia, E., Wollmer, M. A., Umbricht, D., de Quervain, D. J. F., Hofmann, M., Maddalena, A., Papassotiropoulos, A., & Nitsch, R. M. (2003). Antibodies against beta-amyloid slow cognitive decline in Alzheimer’s disease. Neuron, 38(4), 547-554. https://doi.org/10.1016/S0896-6273(03)00294-0   edoc
Majores, M., Kolsch, H., Bagli, M., Papassotiropoulos, A., Lohmann, P. L., Schmitz, S., Rao, M. L., Maier, W., & Heun, R. (2002). Cathepsin D : screening for new polymorphisms using single-strand conformation polymorphism analysis. International Journal of Molecular Medicine, 9(2), 185-187.   edoc
Kockler, M., Nitardy, A., Papassotiropoulos, A., Ptok, U., Maier, W., & Heun, R. (2002). Physical disorders and causes of death in relatives of Alzheimer’s disease patients. International Journal of Geriatric Psychiatry, 17(4), 335-342.   edoc
Papassotiropoulos, A., Lütjohann, D., Bagli, M., Locatelli, S., Jessen, F., Buschfort, R., Ptok, U., Björkhem, I., von Bergmann, K., & Heun, R. (2002). 24S-hydroxycholesterol in cerebrospinal fluid is elevated in early stages of dementia. Journal of Psychiatric Research, 36(1), 27-32.   edoc
Papassotiropoulos, A., & Hock, C. (2002). Biochemical markers of Alzheimer’s disease : wish and reality. Neurobiology of aging. Elsevier Science.   edoc
Wollmer, M. A., Papassotiropoulos, A., Streffer, J. R., Grimaldi, L. M. E., Kapaki, E., Salani, G., Paraskevas, G. P., Maddalena, A., de Quervain, D., Bieber, C., Umbricht, D., Lemke, U., Bosshardt, S., Degonda, N., Henke, K., Hegi, T., Jung, H. H., Pasch, T., Hock, C., & Nitsch, R. M. (2002). Genetic polymorphisms and cerebrospinal fluid levels of tissue inhibitor of metalloproteinases 1 in sporadic Alzheimer’s disease. Psychiatric Genetics, 12(3), 155-160.   edoc
Papassotiropoulos, A., Lewis, H. D., Bagli, M., Jessen, F., Ptok, U., Schulte, A., Shearman, M. S., & Heun, R. (2002). Cerebrospinal fluid levels of beta-amyloid(42) in patients with Alzheimer’s disease are related to the exon 2 polymorphism of the cathepsin D gene. NeuroReport, 13(10), 1291-1294.   edoc
Hock, C., Konietzko, U., Papassotiropoulos, A., Wollmer, A., Streffer, J., von Rotz, R. C., Davey, G., Moritz, E., & Nitsch, R. M. (2002). Generation of antibodies specific for beta-amyloid by vaccination of patients with Alzheimer disease. Nature Medicine, 8(11), 1270-1275.   edoc
Kölsch, H., Ptok, U., Bagli, M., Papassotiropoulos, A., Schmitz, S., Barkow, K., Kockler, M., Rao, M. L., Maier, W., & Heun, R. (2001). Gene polymorphisms of interleukin-1alpha influence the course of Alzheimer’s disease. Annals of Neurology, 49(6), 818-819.   edoc
Heun, R., Papassotiropoulos, A., Jessen, F., Maier, W., & Breitner, J. C. (2001). A family study of Alzheimer disease and early- and late-onset depression in elderly patients. Archives of General Psychiatry, 58(2), 190-196.   edoc
Ptok, U., Papassotiropoulos, A., & Heun, R. (2001). Mental health in spouses of patients with gerontopsychiatric disorders. International Journal of Geriatric Psychiatry, 16(10), 1014-1016.   edoc
Jessen, F., Kucharski, C., Fries, T., Papassotiropoulos, A., Hoenig, K., Maier, W., & Heun, R. (2001). Sensory gating deficit expressed by a disturbed suppression of the P50 event-related potential in patients with Alzheimer’s disease. American Journal of Psychiatry, 158(8), 1319-1321.   edoc
Jessen, F., Flacke, S., Granath, D. O., Manka, C., Scheef, L., Papassotiropoulos, A., Schild, H. H., & Heun, R. (2001). Encoding and retrieval related cerebral activation in continuous verbal recognition. Cognitive Brain Research, 12(2), 199-206.   edoc
Ptok, U., Papassotiropoulos, A., Maier, W., & Heun, R. (2001). Seasonal distribution of births in patients with Alzheimer’s disease and elderly depressive patients. European Psychiatry, 16(3), 157-161.   edoc
Papassotiropoulos, A., Hock, C., & Nitsch, R. M. (2001). Genetics of interleukin 6 : implications for Alzheimer’s disease. Neurobiology of Aging, 22(6), 863-871.   edoc
Ptok, U., Seeher, C., Jessen, F., Papassotiropoulos, A., & Heun, R. (2001). Inter-rater reliability of family history information on psychiatric disorders in relatives. European Archives of Psychiatry and Clinical Neuroscience, 251(6), 279-283.   edoc
Papassotiropoulos, A., Bagli, M., Becker, K., Jessen, F., Maier, W., Rao, M. L., Ludwig, M., & Heun, R. (2000). No association between an intronic biallelic polymorphism of the FE65 gene and Alzheimer’s disease. International Journal of Molecular Medicine, 6(5), 587-589.   edoc
Papassotiropoulos, A., Bagli, M., Kurz, A., Kornhuber, J., Förstl, H., Maier, W., Pauls, J., Lautenschlager, N., & Heun, R. (2000). A genetic variation of cathepsin D is a major risk factor for Alzheimer’s disease. Annals of Neurology, 47(3), 399-403.   edoc
Bagli, M., Papassotiropoulos, A., Jessen, F., Rao, M. L., Maier, W., & Heun, R. (2000). Gene-gene interaction between interleukin-6 and alpha2-macroglobulin influences the risk for Alzheimer’s disease. Annals of Neurology, 47(1), 138-139.   edoc
Lütjohann, D., Papassotiropoulos, A., Björkhem, I., Locatelli, S., Bagli, M., Oehring, R. D., Schlegel, U., Jessen, F., Rao, M. L., von Bergmann, K., & Heun, R. (2000). Plasma 24S-hydroxycholesterol (cerebrosterol) is increased in Alzheimer and vascular demented patients. Journal of Lipid Research, 41(2), 195-198.   edoc | Open Access
Papassotiropoulos, A., Lütjohann, D., Bagli, M., Locatelli, S., Jessen, F., Rao, M. L., Maier, W., Björkhem, I., von Bergmann, K., & Heun, R. (2000). Plasma 24S-hydroxycholesterol : a peripheral indicator of neuronal degeneration and potential state marker for Alzheimer’s disease. NeuroReport, 11(9), 1959-1962.   edoc
Heun, R., Papassotiropoulos, A., & Ptok, U. (2000). Subthreshold depressive and anxiety disorders in the elderly. European Psychiatry, 15(3), 173-182.   edoc
Bagli, M., Papassotiropoulos, A., Knapp, M., Jessen, F., Luise Rao, M., Maier, W., & Heun, R. (2000). Association between an interleukin-6 promoter and 3’ flanking region haplotype and reduced Alzheimer’s disease risk in a German population. Neuroscience Letters, 283(2), 109-112.   edoc
Papassotiropoulos, A., Bagli, M., Jessen, F., Frahnert, C., Rao, M. L., Maier, W., & Heun, R. (2000). Confirmation of the association between bleomycin hydrolase genotype and Alzheimer’s disease. Molecular Psychiatry, 5(2), 213-215.   edoc
Schröder, R., Vielhaber, S., Wiedemann, F. R., Kornblum, C., Papassotiropoulos, A., Broich, P., Zierz, S., Elger, C. E., Reichmann, H., Seibel, P., Klockgether, T., & Kunz, W. S. (2000). New insights into the metabolic consequences of large-scale mtDNA deletions : a quantitative analysis of biochemical, morphological, and genetic findings in human skeletal muscle. Journal of Neuropathology and Experimental Neurology, 59(5), 353-360.   edoc
Papassotiropoulos, A., Bagli, M., Jessen, F., Maier, W., Förstl, H., Kurz, A., & Heun, R. (2000). Interaction of two genes possibly involved in the regulation of the amyloid precursor protein (APP) processing. Molecular Psychiatry, 5(3), 240-241.   edoc
Jessen, F., Heun, R., Erb, M., Granath, D. O., Klose, U., Papassotiropoulos, A., & Grodd, W. (2000). The concreteness effect : evidence for dual coding and context availability. Brain and Language, 74(1), 103-112.   edoc
Majores, M., Bagli, M., Papassotiropoulos, A., Schwab, S. G., Jessen, F., Rao, M. L., Maier, W., & Heun, R. (2000). Allelic association between the D10S1423 marker and Alzheimer’s disease in a German population. Neuroscience Letters, 289(3), 224-226.   edoc
Schmidt, S., Papassotiropoulos, A., Bagli, M., Harzheim, M., Heun, R., & Klockgether, T. (2000). No association of serum levels of interleukin-6 and its soluble receptor components with a genetic variation in the 3’flanking region of the interleukin-6 gene in patients with multiple sclerosis. Neuroscience Letters, 294(3), 139-142.   edoc
Jessen, F., Block, W., Träber, F., Keller, E., Flacke, S., Papassotiropoulos, A., Lamerichs, R., Heun, R., & Schild, H. H. (2000). Proton MR spectroscopy detects a relative decrease of N-acetylaspartate in the medial temporal lobe of patients with AD. Neurology, 55(5), 684-688.   edoc
Finckh, U., von der Kammer, H., Velden, J., Michel, T., Andresen, B., Deng, A., Zhang, J., Müller-Thomsen, T., Zuchowski, K., Menzer, G., Mann, U., Papassotiropoulos, A., Heun, R., Zurdel, J., Holst, F., Benussi, L., Stoppe, G., Reiss, J., Miserez, A. R., Staehelin, H. B., Rebeck, G. W., Hyman, B. T., Binetti, G., Hock, C., Growdon, J. H., & Nitsch, R. M. (2000). Genetic association of a cystatin C gene polymorphism with late-onset Alzheimer disease. Archives of Neurology, 57(11), 1579-1583.   edoc
Heun, R., Kockler, M., & Papassotiropoulos, A. (2000). Distinction of early- and late-onset depression in the elderly by their lifetime symptomatology. International Journal of Geriatric Psychiatry, 15(12), 1138-1142.   edoc
Schulze, T. G., Müller, D. J., Krauss, H., Scherk, H., Ohlraun, S., Syagailo, Y. V., Windemuth, C., Neidt, H., Grässle, M., Papassotiropoulos, A., Heun, R., Nöthen, M. M., Maier, W., Lesch, K. P., & Rietschel, M. (2000). Association between a functional polymorphism in the monoamine oxidase A gene promoter and major depressive disorder. American Journal of Medical Genetics, 96(6), 801-803.   edoc
Bagli, M., Papassotiropoulos, A., Jessen, F., Schmitz, S., Rao, M. L., Maier, W., & Heun, R. (2000). Identical distribution of the alpha 2-macroglobulin pentanucleotide deletion in subjects with Alzheimer disease and controls in a German population. American Journal of Medical Genetics, 96(6), 775-777.   edoc
Ptok, U., Papassotiropoulos, A., Maier, W., & Heun, R. (2000). Advanced parental age : a risk factor for Alzheimer’s disease or depression in the elderly?. International Psychogeriatrics, 12(4), 445-451.   edoc
Kühn, K. U., Meyer, K., Nöthen, M. M., Gänsicke, M., Papassotiropoulos, A., & Maier, W. (1999). Allelic variants of dopamine receptor D4 (DRD4) and serotonin receptor 5HT2c (HTR2c) and temperament factors : replication tests. American Journal of Medical Genetics, 88(2), 168-172.   edoc
Bagli, M., Papassotiropoulos, A., Schwab, S. G., Jessen, F., Rao, M. L., Maier, W., & Heun, R. (1999). No association between an intronic polymorphism in the presenilin-1 gene and Alzheimer disease in a German population. Journal of the Neurological Sciences, 167(1), 34-36.   edoc
Papassotiropoulos, A., Heun, R., & Maier, W. (1999). The impact of dementia on the detection of depression in elderly subjects from the general population. Psychological Medicine, 29(1), 113-120.   edoc
Papassotiropoulos, A., Bagli, M., Jessen, F., Rao, M. L., Schwab, S. G., & Heun, R. (1999). Early-onset and late-onset depression are independent of the genetic polymorphism of apolipoprotein E. Dementia and Geriatric Cognitive Disorders, 10(4), 258-261. https://doi.org/10.1159/000017129   edoc | Open Access
Schwab, S. G., Bagli, M., Papassotiropoulos, A., Jessen, F., Maier, W., Rao, M. L., & Heun, R. (1999). Alpha-1-antichymotrypsin gene polymorphism and risk for sporadic Alzheimer’s disease in a German population. Dementia and Geriatric Cognitive Disorders, 10(6), 469-472. https://doi.org/10.1159/000017191   edoc | Open Access
Papassotiropoulos, A., Hawellek, B., Frahnert, C., Rao, G. S., & Rao, M. L. (1999). The risk of acute suicidality in psychiatric inpatients increases with low plasma cholesterol. Pharmacopsychiatry, 32(1), 1-4.   edoc
Papassotiropoulos, A., Bagli, M., Jessen, F., Bayer, T. A., Maier, W., Rao, M. L., & Heun, R. (1999). A genetic variation of the inflammatory cytokine interleukin-6 delays the initial onset and reduces the risk for sporadic Alzheimer’s disease. Annals of Neurology, 45(5), 666-668.   edoc
Papassotiropoulos, A., & Heun, R. (1999). Detection of subthreshold depression and subthreshold anxiety in the elderly. International Journal of Geriatric Psychiatry, 14(8), 643-650.   edoc
Papassotiropoulos, A., Bagli, M., Feder, O., Jessen, F., Maier, W., Rao, M. L., Ludwig, M., Schwab, S. G., & Heun, R. (1999). Genetic polymorphism of cathepsin D is strongly associated with the risk for developing sporadic Alzheimer’s disease. Neuroscience Letters, 262(3), 171-174.   edoc
Papassotiropoulos, A., & Heun, R. (1999). Screening for depression in the elderly : a study on misclassification by screening instruments and improvement of scale performance. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 23(3), 431-446.   edoc
Heun, R., Klose, U., Jessen, F., Erb, M., Papassotiropoulos, A., Lotze, M., & Grodd, W. (1999). Functional MRI of cerebral activation during encoding and retrieval of words. Human Brain Mapping, 8(4), 157-169.   edoc
Rao, M. L., Hawellek, B., Papassotiropoulos, A., Deister, A., & Frahnert, C. (1998). Upregulation of the platelet Serotonin2A receptor and low blood serotonin in suicidal psychiatric patients. Neuropsychobiology, 38(2), 84-89. https://doi.org/10.1159/000026522   edoc | Open Access
Heun, R., Müller, H., & Papassotiropoulos, A. (1998). Differential validity of informant-based diagnoses of dementia and depression in index subjects and in their first-degree relatives. Social Psychiatry and Psychiatric Epidemiology, 33(10), 510-513.   edoc
Heun, R., Papassotiropoulos, A., & Jennssen, F. (1998). The validity of psychometric instruments for detection of dementia in the elderly general population. International Journal of Geriatric Psychiatry, 13(6), 368-380.   edoc
Papassotiropoulos, A., Heun, R., & Maier, W. (1997). Age and cognitive impairment influence the performance of the General Health Questionnaire. Comprehensive Psychiatry, 38(6), 335-340.   edoc
Papassotiropoulos, A., Ludwig, M., Naib-Majani, W., & Rao, G. S. (1996). Induction of apoptosis and secondary necrosis in rat dorsal root ganglion cell cultures by oxidized low density lipoprotein. Neuroscience Letters, 209(1), 33-36.   edoc
Rao, M. L., Pelzer, E., Papassotiropoulos, A., Tiemeier, H., Jönck, L., & Möller, H. J. (1996). Selective slow-wave sleep deprivation influences blood serotonin profiles and serum melatonin concentrations in healthy subjects. Biological Psychiatry, 40(7), 664-667.   edoc
Rao, M. L., Bräunig, P., & Papassotiropoulos, A. (1994). Autoaggressive behavior is closely related to serotonin availability in schizoaffective disorder. Pharmacopsychiatry, 27(5), 202-206.   edoc