Forschung
Innerhalb der Psychosomatik untersuchen wir, was eine gute Behandlung ausmacht – evidenzbasiert, kontextsensitiv und patientenzentriert.
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Unsere Forschungsprojekte
The best treatment option(s) for patients with chronic primary pain: A network meta-analysis
The Pain Net is an international research network dedicated to identifying the most effective treatment options for patients living with chronic primary pain conditions. The establishment of a large database enables the conductance of multiple network meta-analyses. Currently, and in a study that is funded by the Swiss National Science Foundation (SNSF), we examine possible predictors for opioid and placebo responses.
Principal Investigators: PD Dr. Cosima Locher and PD Dr. Helen Koechlin
Team members: Prof. Antonia Barke, Dr. Beatrice Korwisi, Dr. Anna Kharko, Dr. Colleen Pawliuk, Iman Ibragic, Kiara Bodonyi, several masterstudents and interns
Link to our study protocol: https://pubmed.ncbi.nlm.nih.gov/31706330/
Link to SNSF portal: https://data.snf.ch/grants/grant/201972
Image by Martin Müller
Conditioned open-label placebos to facilitate opioid reduction in patients with chronic noncancer pain: A randomized controlled trial
In a controlled clinical trial at the University Hospital Zurich, we examine whether open-label placebos are helpful in the reduction of opioid medication in patients with chronic noncancer pain. This study is sponsored by the Swiss National Science Foundation (SNSF).
Principal Investigator: PD Dr. Cosima Locher
Team members: Kiara Bodonyi, Sophie Rosch, Nina Fritschi, Tina Kamer
Link to the project: https://www.usz.ch/studie/mind-body-management-ein-ansatz-der-sie-bei-der-reduktion-von-opioiden-unterstuetzt/
Link to SNSF portal: https://data.snf.ch/grants/grant/201972
Reality check: Bodily distress syndrome in general practice
In general practice, patients presenting with bodily distress syndromes pose a considerable challenge. Studies suggest that up to 30% of consultations concern symptoms that exist independent of a clear aetiology. In this project, we closely cooperate with clinical partners such as mediX Zürich. In one of our on-going studies, we investigate the impact of a targeted communication training for general practitioners treating patients with bodily distress syndromes.
Principal Investigators: PD Dr. Cosima Locher and Prof. Dr. Stefan Büchi
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Women’s Health: Examining subjective illness experiences and innovative treatment approaches in women living with premenstrual syndrome
In this project, we focus on women’s health. In a large clinical trial, we found that open-label placebos are effective for the treatment of premenstrual syndrome (PMS). In an on-going focus group study, we evaluateexperiences, attitudes and suggestions of teenagers and young women regarding their first visit to a gynaecologist.
Principal Investigators: Dr. Antje Frey Nascimento and PD Dr. Cosima Locher
Link to our clinical trial: https://ebm.bmj.com/content/early/2025/03/05/bmjebm-2024-112875.abstract
Link to our focus group: https://osf.io/dvznu
Image by Martin Müller
The rapid advancement of artificial intelligence (AI) technologies has revolutionized various fields, including mental health care. Generative AI, which refers to systems capable of generating human-like text, images, or other data, offers new possibilities for mental health assessment, diagnosis, and treatment approaches. However, there is a lack of qualitative work on generative AI, especially in general practice and psychotherapy. In the past, we explored the opinions of healthcare professionals and psychotherapists about the use of generative AI. The next step will be to explore how AI can shape clinical pain management.
Principal Investigators: Prof. Charlotte Blease and PD Dr. Cosima Locher
Collaborators: Dr. Anna Kharko, Dr. Maria Hägglund, Dr. Josefin Hagstrom, Prof. Jens Gaab
Link to our most recent study: https://pmc.ncbi.nlm.nih.gov/articles/PMC11429366/
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